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Fluoxetine Indication.
For the treatment of depression, obsessive compulsive disorder, and bulimia nervosa.
Fluoxetine Contraindications.
Fluoxetine is contraindicated in patients known to be hypersensitive to it.
Monoamine oxidase inhibitors. There have been reports of serious, sometimes fatal, reactions (including hyperthermia, rigidity, myoclonus, autonomic instability with possible rapid fluctuations of vital signs, and mental status changes that include extreme agitation progressing to delirium and coma) in patients receiving fluoxetine in combination with a monoamine oxidase inhibitor (MAOI), and in patients who have recently discontinued fluoxetine and are then started on an MAOI. Some cases presented with features resembling neuroleptic malignant syndrome. Therefore, Fluoxetine should not be used in combination with an MAOI, or within a minimum of 14 days of discontinuing therapy with an MAOI. Since fluoxetine and its major metabolite have very long elimination half-lives, at least 5 weeks (perhaps longer, especially if fluoxetine has been prescribed chronically and/or at higher doses) should be allowed after stopping Fluoxetine before starting an MAOI.
Thioridazine. Thioridazine should not be administered with Fluoxetine or within a minimum of 5 weeks after Fluoxetine has been discontinued .
Fluoxetine Prescription.
Fluoxetine is prescribed to treat depression, obsessive-compulsive disorder (bothersome thoughts that won't go away and the need to perform certain actions over and over), some eating disorders, and panic attacks (sudden, unexpected attacks of extreme fear and worry about these attacks). Fluoxetine is used to relieve the symptoms of premenstrual dysphoric disorder, including mood swings, irritability, bloating, and breast tenderness. Fluoxetine is in a class of prescriptions called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.
The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
How should Fluoxetine be used?
Fluoxetine comes as a capsule, a tablet, a delayed-release (long-acting) capsule, and a solution (liquid) to take by mouth. Fluoxetine may be taken with or without food. Fluoxetine (Sarafem) comes as a capsule to take by mouth. Fluoxetine (Fluoxetine) capsules, tablets, and liquid are usually taken once a day in the morning or twice a day, in the morning and at noon. Fluoxetine delayed-released capsules are usually taken once a week. Fluoxetine (Sarafem) is usually taken once a day, either every day of the month or on certain days of the month. Take fluoxetine at around the same time(s) every day.
Your doctor may start you on a low dose of fluoxetine and gradually increase your dose.
It may take 4 to 5 weeks or longer before you feel the full benefit of fluoxetine.
Fluoxetine, an antidepressant agent belonging to the selective serotonin reuptake inhibitors (SSRIs), is used to treat depression, bulimia nervosa, premenstrual dysphoric disorder, panic disorder and post-traumatic stress. According to the amines hypothesis, a functional decrease in the activity of amines, such as serotonin and norepinephrine, would result in depression; a functional increase of the activity of these amines would result in mood elevation. Fluoxetine's effects are thought to be associated with the inhibition of 5HT receptor, which leads to an increase of serotonin level.
Fluoxetine side effects.
- changes in sex drive or ability;
- coma (loss of consciousness for a period of time);
- confusion;
- difficulty breathing or swallowing;
- dizziness;
- drowsiness;
- dry mouth;
- excessive sweating;
- fainting;
- fever;
- hives;
- joint pain;
- loss of appetite;
- nausea;
- nervousness;
- rapid, irregular, or pounding heartbeat;
- rash;
- seeing things or hearing voices that do not exist (hallucinating);
- seizures;
- sore throat;
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs;
- uncontrollable shaking of a part of the body;
- unresponsiveness;
- unsteadiness;
- weakness;
- weight loss;
