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Ethambutol Indication.
For use, as an adjunct, in the treatment of pulmonary tuberculosis.
Ethambutol Contraindications.
Ethambutol is contraindicated in patients who are known to be hypersensitive to Ethambutol. It is also contraindicated in patients with known optic neuritis unless clinical judgment determines that it may be used. Ethambutol is contraindicated in patients who are unable to appreciate and report visual side effects or changes in vision (eg, young children, unconscious patients).
Ethambutol Prescription.
Ethambutol eliminates certain bacteria that cause tuberculosis (TB). It is prescribed with other medicines to treat tuberculosis and to prevent you from giving the infection to others.
An antitubercular agent that inhibits the transfer of mycolic acids into the cell wall of the tubercle bacillus. It may also inhibit the synthesis of spermidine in mycobacteria. The action is usually bactericidal, and the drug can penetrate human cell membranes to exert its lethal effect. (From Smith and Reynard, Textbook of Pharmacology, 1992, p863)
How should Ethambutol be used?
Ethambutol comes as a tablet to take by mouth. It usually is taken once a day in the morning.
Ethambutol is an oral chemotherapeutic agent which is specifically effective against actively growing microorganisms of the genus Mycobacterium, including M. tuberculosis. Ethambutol inhibits RNA synthesis and decreases tubercle bacilli replication. Nearly all strains of M. tuberculosis and M. kansasii as well as a number of strains of MAC are sensitive to ethambutol.
Ethambutol side effects.
- blurred vision;
- inability to see the colors red and green;
- itching;
- loss of appetite;
- numbness and tingling in the hands or feet;
- skin rash;
- sudden changes in vision;
- upset stomach;
- vomiting;
