Dutasteride Indication.
For the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland.
Dutasteride Contraindications.
Duagen is contraindicated for use in women and children. Duagen is contraindicated for patients with known hypersensitivity to dutasteride, other A-reductase inhibitors, or any component of the preparation.
Dutasteride Prescription.
Dutasteride is prescribed to treat an enlarged prostate (benign prostatic hyperplasia, or BPH). Dutasteride is in a class of prescriptions called 5-alpha reductase inhibitors. It works by blocking the production of a natural substance that enlarges the prostate. This shrinks the prostate, relieves symptoms of BPH, such as frequent and difficult urination, and decreases the chance that surgery will be needed to treat this condition.
Dutasteride belongs to a class of drugs called 5-alpha-reductase inhibitors, which block the action of the 5-alpha-reductase enzymes that convert testosterone into dihydrotestosterone (DHT). Finasteride also belongs to this group. Dutasteride inhibits both isoforms of 5-alpha reductase, while finasteride inhibits only one. But a clinical study done by GlaxoSmithKline, the EPICS trial, did not find dutasteride to be more effective than finasteride in treating BPH.
How should Dutasteride be used?
Dutasteride comes as a capsule to take by mouth. It is usually taken once a day with or without food. To help you remember to take dutasteride, take it around the same time every day.
Swallow the capsules whole; do not split, chew, or crush them.
Dutasteride is a synthetic 4-azasteroid compound that is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5 alpha-reductase (5AR), an intracellular enzyme that converts testosterone to 5 alpha-dihydrotestosterone (DHT). Dutasteride is indicated for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland.
Dutasteride side effects.
- breast tenderness or enlargement;
- decrease in sex drive;
- difficulty ejaculating;
- inability to have or maintain an erection;
